Title : Effect of the histamine-2 agonist impromidine on stem cell proliferation of rat oxyntic mucosa.

Pub. Date : 1995 Apr

PMID : 7610344






3 Functional Relationships(s)
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1 BACKGROUND: The trophic effect of gastrin on the histamine-containing enterochromaffin-like cell is pronounced but on the stem cell of the oxyntic mucosa it is only modest. Histamine gastrin Rattus norvegicus
2 In the rat, gastrin stimulates acid secretion mainly by releasing histamine from enterochromaffin-like cells. Histamine gastrin Rattus norvegicus
3 This study was designed to test the hypothesis that the trophic effect of gastrin on stem cells is also mediated by histamine released from the enterochromaffin-like cell. Histamine gastrin Rattus norvegicus