Title : Structure/function relationships of mitochondrial monoamine oxidase A and B chimeric forms.

Pub. Date : 1995 Jun 15

PMID : 7601156






1 Functional Relationships(s)
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1 Whereas exchange of the ADP-binding sequence did not modify the catalytic properties of either MAO isoforms, chimeras with increasing length of the NH2-terminus of MAO-A (up to residue 256) showed a marked decrease in affinity towards the MAO-B substrate phenylethylamine and the inhibitor N-(2-aminoethyl)-5-chloro-2-pyridine carboxamide . Phenethylamines monoamine oxidase B Homo sapiens