Title : Effect of a gonadotropin releasing hormone analog on an experimental ovarian tumor: direct and indirect actions.

Pub. Date : 1995

PMID : 7596232






2 Functional Relationships(s)
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1 Estradiol and progesterone in portal blood, which collects the steroids secreted by the luteoma, were significantly reduced by GnRH-a treatment in both models. Steroids gonadotropin releasing hormone 1 Rattus norvegicus
2 These results clearly show that the GnRH-a is effective in inhibiting tumor growth or reducing its volume, when already developed; furthermore, it suppresses tumor steroid hormone production. Steroids gonadotropin releasing hormone 1 Rattus norvegicus