Title : Coupling of the proto-oncogene product c-Cbl to the epidermal growth factor receptor.

Pub. Date : 1995 Oct 27

PMID : 7592693






2 Functional Relationships(s)
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1 Both Grb2 and EGF receptors are released from Cbl in the presence of a proline-rich peptide that binds the NH2-terminal SH3 domain of Grb2. Proline Cbl proto-oncogene Homo sapiens
2 These results indicate that autophosphorylated EGF receptors associate with the SH2 domain of Grb2, which is complexed through its SH3 domain with proline-rich regions of Cbl. Proline Cbl proto-oncogene Homo sapiens