Title : Coupling of the proto-oncogene product c-Cbl to the epidermal growth factor receptor.

Pub. Date : 1995 Oct 27

PMID : 7592693






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Both Grb2 and EGF receptors are released from Cbl in the presence of a proline-rich peptide that binds the NH2-terminal SH3 domain of Grb2. Proline growth factor receptor bound protein 2 Homo sapiens
2 Both Grb2 and EGF receptors are released from Cbl in the presence of a proline-rich peptide that binds the NH2-terminal SH3 domain of Grb2. Proline growth factor receptor bound protein 2 Homo sapiens
3 These results indicate that autophosphorylated EGF receptors associate with the SH2 domain of Grb2, which is complexed through its SH3 domain with proline-rich regions of Cbl. Proline growth factor receptor bound protein 2 Homo sapiens