Title : The effect of a naphthalene derivative, TEI-6472, on histamine release and tyrosine phosphorylation in rat basophilic leukemia cells.

Pub. Date : 1995 May

PMID : 7591368






2 Functional Relationships(s)
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1 When RBL-2H3 cells are sensitized with IgE antibody and subsequently stimulated by an antigen, significant histamine release and the tyrosine phosphorylation of several proteins are observed. Histamine RB transcriptional corepressor like 2 Rattus norvegicus
2 Preincubation for 10 min with 100 microM TEI-6472 caused significant inhibition of Fc epsilon RI-mediated histamine release from RBL-2H3 cells. Histamine RB transcriptional corepressor like 2 Rattus norvegicus