Title : Exacerbation of acetaminophen hepatotoxicity by thalidomide and protection by nicotinic acid amide.

Pub. Date : 1995 Oct

PMID : 7590113






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The Thal-induced exacerbation of AAP hepatotoxicity was completely inhibited by nicotinic acid amide, a selective inhibitor of poly(ADP-ribose) polymerase (PARP) (P < 0.0001), suggesting a possible influence of Thal on the hepatic metabolism of NAD-adenoribosylation. Niacinamide poly (ADP-ribose) polymerase family, member 1 Mus musculus
2 The Thal-induced exacerbation of AAP hepatotoxicity was completely inhibited by nicotinic acid amide, a selective inhibitor of poly(ADP-ribose) polymerase (PARP) (P < 0.0001), suggesting a possible influence of Thal on the hepatic metabolism of NAD-adenoribosylation. Niacinamide poly (ADP-ribose) polymerase family, member 1 Mus musculus