Title : DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective.

Pub. Date : 1995 Oct 16

PMID : 7588628






1 Functional Relationships(s)
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1 Cisplatin treatment of Epstein-Barr virus-immortalized human B lymphoblastoid cell lines (LCLs) results in p53-mediated apoptosis which occurs largely in a population of cells at the G1/S boundary of the cell cycle. Cisplatin tumor protein p53 Homo sapiens