Title : Ornithine decarboxylase transformation of NIH/3T3 cells is mediated by altered epidermal growth factor receptor activity.

Pub. Date : 1995 Nov 15

PMID : 7585601






1 Functional Relationships(s)
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1 Disruption of EGF-R mediated signal transduction in NODC-2 cells both by treatment with tyrphostin-25 or by transfection with a vector expressing a dominant negative EGF-R mutant resulted in reacquisition of contact-inhibited growth and suppression of anchorage-independent, clonogenic growth in soft agar. Tyrphostins epidermal growth factor receptor Mus musculus