Title : IgE-induced changes in human basophil cyclic AMP levels.

Pub. Date : 1978

PMID : 75852






2 Functional Relationships(s)
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1 We studied a unique patient with 77% basophils, not different from normal by a number of criteria, in order to measure the changes in cyclic AMP level associated with IgE-mediated histamine release. Histamine immunoglobulin heavy constant epsilon Homo sapiens
2 In accordance with previous hypothesis and circumstantial evidence, anti-IgE challenge led to a significant fall in the cyclic AMP level which preceded histamine release. Histamine immunoglobulin heavy constant epsilon Homo sapiens