Title : Studies on the role of 5-HT1A autoreceptors and alpha 1-adrenoceptors in the inhibition of 5-HT release--I. BMY7378 and prazosin.

Pub. Date : 1995 Jun

PMID : 7566497






2 Functional Relationships(s)
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1 The BMY7378- and 8-OH-DPAT-induced inhibition of 5-HT release were reversed by a 40 min pre-treatment with either (+/-)pindolol (8 mg/kg, s.c.) or WAY-100635 (0.3 mg/kg, s.c.), to block 5-HT1A autoreceptors. Pindolol 5-hydroxytryptamine receptor 1A Homo sapiens
2 These data support the usefulness of pindolol, as well as the more specific compound WAY-100635, to block 5-HT1A autoreceptors. Pindolol 5-hydroxytryptamine receptor 1A Homo sapiens