Title : Structure-activity relationship of novel pentapeptide neuropeptide Y receptor antagonists is consistent with a noncontinuous epitope for ligand-receptor binding.

Pub. Date : 1995 Sep

PMID : 7565622






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The inactive NPY carboxyl-terminal pentapeptide (Thr-Arg-Gln-Arg-Tyr-NH2; IC50 > 100 microM) was modified by replacing threonine with an aromatic amino acid and glutamine with leucine. Threonine neuropeptide Y Homo sapiens
2 The inactive NPY carboxyl-terminal pentapeptide (Thr-Arg-Gln-Arg-Tyr-NH2; IC50 > 100 microM) was modified by replacing threonine with an aromatic amino acid and glutamine with leucine. Threonine neuropeptide Y Homo sapiens