Title : The role of the YAP1 and YAP2 genes in the regulation of the adaptive oxidative stress responses of Saccharomyces cerevisiae.

Pub. Date : 1995 May

PMID : 7565103






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We show that yeast mutants deleted for either the YAP1 or the YAP2 genes are hypersensitive to oxidants, particularly H2O2, and that these genes play a role in regulating the induction of the H2O2 adaptive stress response in Saccharomyces cerevisiae. Hydrogen Peroxide DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C
2 We show that yeast mutants deleted for either the YAP1 or the YAP2 genes are hypersensitive to oxidants, particularly H2O2, and that these genes play a role in regulating the induction of the H2O2 adaptive stress response in Saccharomyces cerevisiae. Hydrogen Peroxide DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C
3 Furthermore, while the H2O2-mediated induction of SSA1 expression is shown to by YAP1 dependent, the heat-shock-mediated induction of the SSA1 gene does not require YAP1. Hydrogen Peroxide DNA-binding transcription factor YAP1 Saccharomyces cerevisiae S288C