Title : Thrombin-bound structures of designed analogs of human fibrinopeptide A determined by quantitative transferred NOE spectroscopy: a new structural basis for thrombin specificity.

Pub. Date : 1995 Oct 6

PMID : 7563081






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Analogs of FpA and FpA Rouen have been designed that include a Pro15 to replace Val15 in natural FpA and to mimic the frequent occurrences of a proline residue at equivalent positions of other protein substrates of thrombin. Proline coagulation factor II, thrombin Homo sapiens