Title : Specificity of p-aminohippurate transport system in the OK kidney epithelial cell line.

Pub. Date : 1995 Sep

PMID : 7562483






3 Functional Relationships(s)
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1 PAH uptake by OK cells from the basal side was inhibited by beta-lactam antibiotics such as benzylpenicillin (PCG) and cefazolin. p-Aminohippuric Acid psoriasis susceptibility 1 candidate 2 Rattus norvegicus
2 The inhibition of PAH uptake by PCG was competitive and the Ki value was calculated as 108.8 microM. p-Aminohippuric Acid psoriasis susceptibility 1 candidate 2 Rattus norvegicus
3 Transcellular transport of PCG across OK cell monolayers occurred unidirectionally from the basal to apical side, and transcellular transport and basolateral uptake were inhibited by PAH, probenecid and beta-lactam antibiotics. p-Aminohippuric Acid psoriasis susceptibility 1 candidate 2 Rattus norvegicus