Title : Interleukin-1-mediated stimulation of prostaglandin E production is without effect on plasminogen activator activity in human granulosa lutein cell cultures.

Pub. Date : 1995 Oct

PMID : 7559890






2 Functional Relationships(s)
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1 The ability of IL-1 to suppress PA activity and to produce PAI-1 persisted in the presence of indomethacin, a potent inhibitor of PG synthesis. Prostaglandins interleukin 1 beta Homo sapiens
2 The present findings suggest a pluripotent response of GLCs to IL-1, characterized by the induction of PAI-1 and the suppression of PA occurring concurrent with, but independent of, PG production. Prostaglandins interleukin 1 beta Homo sapiens