Title : Introduction of a murine p53 mutation corresponding to human codon 249 into a murine hepatocyte cell line results in growth advantage, but not in transformation.

Pub. Date : 1995 Oct

PMID : 7557882






1 Functional Relationships(s)
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1 The p53 gene is frequently mutated in human tumors; in hepatocellular carcinomas, there is a high frequency of a specific mutation at codon 249 in regions with significant aflatoxin exposure. Aflatoxins tumor protein p53 Homo sapiens