Title : Evidence for a protein synthesis-dependent and -independent TNF alpha cytolytic mechanism.

Pub. Date : 1995 Sep

PMID : 7545633






1 Functional Relationships(s)
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1 The oxygen free radical scavengers, dimethylsulphoxide (0.2-0.4 M) and glutathione (2 x 10(-6)-10(-5) M) block the TNF alpha-mediated cytolysis of target cells in the absence of protein synthesis inhibitors, but not in the presence of EM or ACT-D. radical tumor necrosis factor Mus musculus