Title : Effect of blockade of nitric oxide synthesis on the renin secretory response to frusemide in conscious rabbits.

Pub. Date : 1995 Jun

PMID : 7543396






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Effect of blockade of nitric oxide synthesis on the renin secretory response to frusemide in conscious rabbits. Furosemide LOW QUALITY PROTEIN: renin Oryctolagus cuniculus
2 In the present study, we investigated the effect of inhibiting nitric oxide synthase on the renin secretory response to frusemide, which stimulates renin secretion by blocking Na(+)-K(+)-2Cl- co-transport in the macula densa. Furosemide LOW QUALITY PROTEIN: renin Oryctolagus cuniculus
3 In the present study, we investigated the effect of inhibiting nitric oxide synthase on the renin secretory response to frusemide, which stimulates renin secretion by blocking Na(+)-K(+)-2Cl- co-transport in the macula densa. Furosemide LOW QUALITY PROTEIN: renin Oryctolagus cuniculus
4 Inhibition of nitric oxide synthase with NG-nitro-L-arginine methyl ester increased mean arterial pressure by 9 mmHg, decreased heart rate and plasma renin activity, and markedly suppressed the renin response to frusemide (from 4.6 +/- 0.7 to 7.6 +/- 1.7, 4.7 +/- 1.0 and 4.6 +/- 0.7 pmol 2 h-1 ml-1 at 15, 30 and 45 min respectively). Furosemide LOW QUALITY PROTEIN: renin Oryctolagus cuniculus