Title : Co-induction of nitric oxide synthase and cyclo-oxygenase: interactions between nitric oxide and prostanoids.

Pub. Date : 1995 Apr

PMID : 7541688






1 Functional Relationships(s)
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1 The co-release of NO and PGI2 induced by LPS is dependent on protein synthesis and occurs after a lag-time of 6-12 h. The formation of COX metabolites has no effect on NOS activity whereas NO inhibits both COX-2 activity and induction. Epoprostenol cytochrome c oxidase II, mitochondrial Rattus norvegicus