Pub. Date : 1995 Mar
PMID : 7538218
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We investigated the inhibitory action of FK506 (0.0005-5 micrograms/ml) on the metabolism of arachidonate 5-lipoxygenase in rat basophilic leukemia-1 cells. | Tacrolimus | arachidonate 5-lipoxygenase | Rattus norvegicus |
2 | These results indicate that FK506 inhibits the production of peptide LTs, LTB4 and 5-HETE by inhibiting 5-lipoxygenase activity in intact cells. | Tacrolimus | arachidonate 5-lipoxygenase | Rattus norvegicus |