Title : Transforming growth factor-beta 1 regulates axon/Schwann cell interactions.

Pub. Date : 1995 Apr

PMID : 7536747






1 Functional Relationships(s)
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1 In the case of purified Schwann cells, treatment with TGF-beta 1 increases their proliferation, and it promotes a pre- or nonmyelinating Schwann cell phenotype characterized by increased NCAM expression, decreased NGF receptor expression, inhibition of the forskolin-mediated induction of the myelin protein P0, and induction of the Schwann cell transcription factor suppressed cAMP-inducible POU protein. Colforsin transforming growth factor beta 1 Homo sapiens