Title : Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction.

Pub. Date : 1995 Feb 27

PMID : 7533107






4 Functional Relationships(s)
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1 Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction. Serine interleukin 6 Homo sapiens
2 Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction. Serine interleukin 6 Homo sapiens
3 We now show that IL-6 triggers a delayed phosphorylation of APRF at serine resudues which can be reversed in vitro by protein phosphatase 2A and is also inhibited by H7. Serine interleukin 6 Homo sapiens
4 Therefore, APRF serine phosphorylation is likely to represent a crucial event in IL-6 signal transduction leading to target gene induction. Serine interleukin 6 Homo sapiens