Title : Regulation of hepatic nitric oxide synthase by reactive oxygen intermediates and glutathione.

Pub. Date : 1995 Feb 1

PMID : 7532384






2 Functional Relationships(s)
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1 Concurrent treatment with TNF alpha and the antioxidant, Trolox, or the iron-chelating agent, desferrioxamine, also reduces NOS activity. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid tumor necrosis factor Rattus norvegicus
2 Trolox and BCNU, combined, blocked TNF alpha stimulation of NOS greater than either agent alone. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid tumor necrosis factor Rattus norvegicus