Title : Active site studies of DT-diaphorase employing artificial flavins.

Pub. Date : 1995 Feb 10

PMID : 7531691






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 NAD(P)H:quinone oxidoreductase (EC 1.6.99.2) (DT-diaphorase) is an FAD-containing enzyme that catalyzes the 2-electron reduction of quinones to hydroquinones using either NADH or NADPH as the electron donor. Flavin-Adenine Dinucleotide NAD(P)H quinone dehydrogenase 1 Homo sapiens
2 The results suggest that DT-diaphorase shows the same properties as the C-C transhydrogenases, and the binding of dicumarol elicits a conformational change or an adjustment in the polarity of the FAD pocket. Flavin-Adenine Dinucleotide NAD(P)H quinone dehydrogenase 1 Homo sapiens