Title : Interleukin-1 activates p54 mitogen-activated protein (MAP) kinase/stress-activated protein kinase by a pathway that is independent of p21ras, Raf-1, and MAP kinase kinase.

Pub. Date : 1994 Dec 16

PMID : 7527398






1 Functional Relationships(s)
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1 Ceramide has been proposed as an intracellular mediator of IL-1 action, but C2-ceramide or sphingosine stimulated predominantly MBP-specific kinase activity in fibroblasts and had no effect in HepG2 cells. Ceramides interleukin 1 alpha Homo sapiens