Title : Acyclic analogue of lipid A stimulates TNF-alpha and arachidonate release via a unique LPS-signaling pathway.

Pub. Date : 1994 Dec 1

PMID : 7525728






2 Functional Relationships(s)
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1 Acyclic analogue of lipid A stimulates TNF-alpha and arachidonate release via a unique LPS-signaling pathway. Lipid A tumor necrosis factor Homo sapiens
2 Co-incubation of PBMC with the specific LPS inhibitor Rhodobacter sphaeroides lipid A inhibited SDZ 280.961-mediated stimulation of TNF-alpha release, indicating that this analogue signals mononuclear cells via a LPS-activated signaling pathway. Lipid A tumor necrosis factor Homo sapiens