Title : Does the insulin-mimetic action of vanadate involve insulin receptor kinase?

Pub. Date : 1993 Nov

PMID : 7523848






4 Functional Relationships(s)
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1 Does the insulin-mimetic action of vanadate involve insulin receptor kinase? Vanadates insulin receptor Rattus norvegicus
2 Effects of vanadate administration on the insulin receptor status in liver were examined in streptozotocin-induced diabetic rats. Vanadates insulin receptor Rattus norvegicus
3 In vitro, vanadate prevented the dephosphorylation of the phosphorylated insulin receptor and increased its tyrosine kinase activity in the absence as well as presence of insulin. Vanadates insulin receptor Rattus norvegicus
4 The findings of this study further support the view that insulin receptor is one of the sites involved in the insulin-mimetic actions of vanadate. Vanadates insulin receptor Rattus norvegicus