Title : Induction of nitric oxide synthase in cultured vascular smooth muscle cells: the role of cyclic AMP.

Pub. Date : 1994 Jun

PMID : 7521256






1 Functional Relationships(s)
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1 Dibutyryl cyclic AMP (db cyclic AMP, 0.1-1 mM), forskolin (1-10 microM) and the phosphodiesterase inhibitor, Ro 20-1724 (1-10 microM), all of which increase intracellular cyclic AMP, had no effect on NO production when added alone but markedly enhanced NO production by IL-1 beta-stimulated VSM cells in a dose-dependent manner. Bucladesine interleukin 1 beta Homo sapiens