Title : Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-alpha and IL-1 beta production by human monocytes.

Pub. Date : 1994 Aug 15

PMID : 7519214






1 Functional Relationships(s)
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1 TNF-alpha and IL-1 beta secretion were completely blocked by protein kinase C (PKC) and cyclic nucleotide-dependent protein kinase inhibitor, H-7, but were not affected by H-89, a specific cyclic nucleotide-dependent protein kinase inhibitor. 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine interleukin 1 beta Homo sapiens