Title : 1462V mutation in the human CYP1A1 gene: lack of correlation with either the Msp I 1.9 kb (M2) allele or CYP1A1 inducibility in a three-generation family of east Mediterranean descent.

Pub. Date : 1994 Feb

PMID : 7516235






1 Functional Relationships(s)
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Protein Name
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1 This latter nucleotide change results in an altered amino acid (462Ile-->Val), which is purported to increase CYP1A1 enzyme activity and mutagenicity towards benzo[a]pyrene about two-fold among Japanese. pyrene cytochrome P450 family 1 subfamily A member 1 Homo sapiens