Title : Effects of guanidino and uremic compounds on nitric oxide pathways.

Pub. Date : 1994 Mar

PMID : 7515129






1 Functional Relationships(s)
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1 L-NMMA and ADMA inhibited endothelium-dependent relaxations (EC50 = 4.7 +/- 1.1 microM and 17.9 +/- 4.9 microM, respectively); methylguanidine caused endothelium-independent contractions and reversed the relaxations to bradykinin and sodium nitroprusside (EC50 > 100 microM); aminoguanidine was without effect. omega-N-Methylarginine kininogen 1 Homo sapiens