Title : Phospholipase A2 enhances [3H]AMPA binding to a putative homomeric GluR-B receptor in the rat spinal cord.

Pub. Date : 1994 Feb 14

PMID : 7508865






3 Functional Relationships(s)
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1 Phospholipase A2 enhances [3H]AMPA binding to a putative homomeric GluR-B receptor in the rat spinal cord. Tritium phospholipase A2 group IB Rattus norvegicus
2 Phospholipase A2 elicited a dose-dependent increase in specific [3H]AMPA binding but not in [3H]kainate binding. Tritium phospholipase A2 group IB Rattus norvegicus
3 Since GluR-B is the only AMPA receptor subunit detectable in the rat spinal cord, and recombinant homomeric GluR-B assemblies do not bind [3H]kainate, these results suggest phospholipase A2 may modulate [3H]AMPA binding to putative homomeric GluR-B receptors. Tritium phospholipase A2 group IB Rattus norvegicus