Title : P-selectin mediates neutrophil rolling on histamine-stimulated endothelial cells.

Pub. Date : 1993 Oct

PMID : 7506064






3 Functional Relationships(s)
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1 P-selectin mediates neutrophil rolling on histamine-stimulated endothelial cells. Histamine selectin P Homo sapiens
2 Here we demonstrate and characterize PMN rolling on monolayers of human umbilical vein endothelial cells (HUVECs) stimulated with histamine to induce surface expression of P-selectin. Histamine selectin P Homo sapiens
3 Rolling adhesion of PMNs on histamine-stimulated HUVECs therefore appears to be completely dependent on endothelial cell P-selectin, with a minor adhesion-stabilizing contribution from intercellular adhesion molecule 1 and beta 2 integrins. Histamine selectin P Homo sapiens