Pub. Date : 1995 Sep 15
PMID : 7502579
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The activity of an upstream repression sequence (URS element) that mediates a 20-fold repression of ENO1 expression in cells grown in a medium containing glucose was characterized. | Peptichemio | phosphopyruvate hydratase ENO1 | Saccharomyces cerevisiae S288C |
| 2 | Sequences that are sufficient for orientation-dependent ENO1 URS element activity were mapped between positions -241 and -126 relative to the ENO1 transcriptional initiation site. | Peptichemio | phosphopyruvate hydratase ENO1 | Saccharomyces cerevisiae S288C |
| 3 | Sequences that are sufficient for orientation-dependent ENO1 URS element activity were mapped between positions -241 and -126 relative to the ENO1 transcriptional initiation site. | Peptichemio | phosphopyruvate hydratase ENO1 | Saccharomyces cerevisiae S288C |
| 4 | The ENO1 URS element repressed transcription of the yeast CYC1 gene when positioned between the CYC1 upstream activation sequences (UAS elements) and TATAAA boxes. | Peptichemio | phosphopyruvate hydratase ENO1 | Saccharomyces cerevisiae S288C |
| 5 | The ENO1 URS element failed to repress transcription of the wild-type yeast enolase gene ENO2; however, expression of an ENO2 gene lacking one of the ENO2 UAS elements was efficiently repressed by the ENO1 URS element, suggesting that the URS element interferes with the transcriptional activation by some, but not all, UAS elements. | Peptichemio | phosphopyruvate hydratase ENO1 | Saccharomyces cerevisiae S288C |
| 6 | The ENO1 URS element failed to repress transcription of the wild-type yeast enolase gene ENO2; however, expression of an ENO2 gene lacking one of the ENO2 UAS elements was efficiently repressed by the ENO1 URS element, suggesting that the URS element interferes with the transcriptional activation by some, but not all, UAS elements. | Peptichemio | phosphopyruvate hydratase ENO1 | Saccharomyces cerevisiae S288C |
| 7 | The ENO1 URS element failed to repress transcription of the wild-type yeast enolase gene ENO2; however, expression of an ENO2 gene lacking one of the ENO2 UAS elements was efficiently repressed by the ENO1 URS element, suggesting that the URS element interferes with the transcriptional activation by some, but not all, UAS elements. | Peptichemio | phosphopyruvate hydratase ENO1 | Saccharomyces cerevisiae S288C |
| 8 | The ENO1 URS element failed to repress transcription of the wild-type yeast enolase gene ENO2; however, expression of an ENO2 gene lacking one of the ENO2 UAS elements was efficiently repressed by the ENO1 URS element, suggesting that the URS element interferes with the transcriptional activation by some, but not all, UAS elements. | Peptichemio | phosphopyruvate hydratase ENO1 | Saccharomyces cerevisiae S288C |
| 9 | The ENO1 URS element failed to repress transcription of the wild-type yeast enolase gene ENO2; however, expression of an ENO2 gene lacking one of the ENO2 UAS elements was efficiently repressed by the ENO1 URS element, suggesting that the URS element interferes with the transcriptional activation by some, but not all, UAS elements. | Peptichemio | phosphopyruvate hydratase ENO1 | Saccharomyces cerevisiae S288C |
| 10 | In contrast to the ENO1 gene, the ENO1 URS element repressed CYC1 and ENO2 expression in cells grown on glucose or glycerol plus lactate. | Peptichemio | phosphopyruvate hydratase ENO1 | Saccharomyces cerevisiae S288C |
| 11 | Evidence is presented that the ENO1 URS element also functions during stationary growth phase. | Peptichemio | phosphopyruvate hydratase ENO1 | Saccharomyces cerevisiae S288C |