Pub. Date : 1995 May
PMID : 7494384
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | 5-HT1A-receptor subtype mediates the effect of fluvoxamine, a selective serotonin reuptake inhibitor, on marble-burying behavior in mice. | Fluvoxamine | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
2 | However, the 5-HT1A antagonist NAN-190 (1-(2-methoxyphenyl)-4-[4-(2-phthalimido)butyl] piperazine) inhibited the suppressive effect of fluvoxamine on the marble-burying. | Fluvoxamine | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
3 | From these results, the 5-HT1A-receptor subtype may be involved in the suppressive effect of fluvoxamine on the marble-burying, but the 5-HT2-receptor subtype is not involved in this effect. | Fluvoxamine | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |