Pub. Date : 1995 Nov
PMID : 7490793
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | This study aimed to assess the possibility of a direct effect of betel-nut alkaloids arecoline and arecaidine on cell proliferation and interleukin-6 (IL-6) production by cultured fibroblasts from human normal gingiva, buccal mucosa and oral submucous fibrosis (OSF) buccal mucosa in vitro. | Arecoline | interleukin 6 | Homo sapiens |
2 | However, two of six individuals" normal buccal mucosa fibroblasts significantly released less IL-6, and some cases of OSF and healthy gingiva exhibited slightly higher levels of IL-6 when cells were exposed to arecoline or arecaidine in cultures. | Arecoline | interleukin 6 | Homo sapiens |
3 | Such findings suggests that arecoline and arecaidine can enhance cell proliferation and affect fibroblasts to synthesize IL-6. | Arecoline | interleukin 6 | Homo sapiens |