Pub. Date : 1995 Oct 24
PMID : 7488039
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity. | sapropterin | nitric oxide synthase 3 | Homo sapiens |
2 | Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity. | sapropterin | nitric oxide synthase 3 | Homo sapiens |
3 | Here, we demonstrated that cys-99 of human endothelial NOS (ecNOS) is critical for BH4 involvement in NOS catalytic activity and stability. | sapropterin | nitric oxide synthase 3 | Homo sapiens |
4 | Here, we demonstrated that cys-99 of human endothelial NOS (ecNOS) is critical for BH4 involvement in NOS catalytic activity and stability. | sapropterin | nitric oxide synthase 3 | Homo sapiens |
5 | Mutation of cys-99 to alanine in ecNOS resulted in loss of catalytic activity which could be restored to the level of wild type by adding a high concentration of exogenous BH4 to the crude extract. | sapropterin | nitric oxide synthase 3 | Homo sapiens |