Title : A tyrphostin-derived inhibitor of protein tyrosine kinases: isolation and characterization.

Pub. Date : 1995 Nov 10

PMID : 7487083






1 Functional Relationships(s)
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1 We recently reported that tyrphostin 23 (3,4-dihydroxybenzylidene malononitrile) is unstable in solution and that some of the degradation products are better inhibitors of the tyrosine kinase activity of Src and the EGF-receptor kinase than the parent compound itself (Ramdas et al., Cancer Res. Tyrphostins SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens