Title : Thiopyranol[2,3,4-c,d]indoles as inhibitors of 5-lipoxygenase, 5-lipoxygenase-activating protein, and leukotriene C4 synthase.

Pub. Date : 1995 Oct 27

PMID : 7473582






1 Functional Relationships(s)
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1 The attachment of an arylacetic or benzoic acid moiety to the thiopyrano[2,3,4-c,d]indole nucleus results in compounds which are highly potent and selective 5-lipoxygenase (5-LO) inhibitors. Benzoic Acid arachidonate 5-lipoxygenase Homo sapiens