Title : Effects of insulin-like growth factor I and interactions with transforming growth factor alpha and LH on proliferation of chicken granulosa cells and production of progesterone in culture.

Pub. Date : 1995 Jul

PMID : 7473417






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 IGF-I stimulated progesterone production from granulosa cells of all the follicles with no change in ED50 value during follicular maturation; however, the maximum response was from cells derived from F1 follicles. Progesterone insulin like growth factor 1 Gallus gallus
2 IGF-I plus LH had an additive effect on progesterone production by cells from all follicles. Progesterone insulin like growth factor 1 Gallus gallus
3 In contrast, TGF-alpha inhibited basal and LH- and IGF-I-stimulated progesterone production. Progesterone insulin like growth factor 1 Gallus gallus