Pub. Date : 1980 Jun
PMID : 7400118
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Reduction of methemoglobin through flavin at the physiological concentration by NADPH-flavin reductase of human erythrocytes. | 4,6-dinitro-o-cresol | hemoglobin subunit gamma 2 | Homo sapiens |
| 2 | The reduction of methemoglobin by NADPH-flavin reductase of human erythrocytes through flavin was studied under various conditions using a reconstituted methemoglobin reductase system. | 4,6-dinitro-o-cresol | hemoglobin subunit gamma 2 | Homo sapiens |
| 3 | The reduction of methemoglobin by NADPH-flavin reductase of human erythrocytes through flavin was studied under various conditions using a reconstituted methemoglobin reductase system. | 4,6-dinitro-o-cresol | hemoglobin subunit gamma 2 | Homo sapiens |
| 4 | The reduction of methemoglobin by the reconstituted enzyme system could be easily detected with flavin at the physiological concentration (e.g., 0.1-1.0 microM), and the rates obtained with 0.1 and 1.0 microM FMN were 0.19 and 2.2 nmol heme reduced per min per ml, respectively, in the absence of oxygen. | 4,6-dinitro-o-cresol | hemoglobin subunit gamma 2 | Homo sapiens |
| 5 | The reduction of methemoglobin by the reconstituted enzyme system with flavin at a physiological concentration proceeded as a zero order reaction. | 4,6-dinitro-o-cresol | hemoglobin subunit gamma 2 | Homo sapiens |
| 6 | These results apparently suggest that the NADPH-flavin reductase system is able to reduce methemoglobin in erythrocytes at a moderate speed with about 1 microM flavin, and the reduction was estimated to vary from less than 1% to about 20% of that by the NADH-cytochrome b5 reductase system with 1 microM cytochrome b5, depending on the uptake of flavin by human erythrocytes. | 4,6-dinitro-o-cresol | hemoglobin subunit gamma 2 | Homo sapiens |
| 7 | These results apparently suggest that the NADPH-flavin reductase system is able to reduce methemoglobin in erythrocytes at a moderate speed with about 1 microM flavin, and the reduction was estimated to vary from less than 1% to about 20% of that by the NADH-cytochrome b5 reductase system with 1 microM cytochrome b5, depending on the uptake of flavin by human erythrocytes. | 4,6-dinitro-o-cresol | hemoglobin subunit gamma 2 | Homo sapiens |