Title : The selective release of phospholipase A2 by resident mouse peritoneal macrophages.

Pub. Date : 1981 Nov 15

PMID : 7340844






4 Functional Relationships(s)
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1 When macrophages are exposed to zymosan in culture, the cellular activity of pH-4.5 phospholipase A2 is diminished in a manner dependent on zymosan concentration and time of exposure, whereas the cellular activities of pH-8.5 phospholipase A2 and phospholipase C remain unchanged. Zymosan phospholipase A2, group IB, pancreas Mus musculus
2 When macrophages are exposed to zymosan in culture, the cellular activity of pH-4.5 phospholipase A2 is diminished in a manner dependent on zymosan concentration and time of exposure, whereas the cellular activities of pH-8.5 phospholipase A2 and phospholipase C remain unchanged. Zymosan phospholipase A2, group IB, pancreas Mus musculus
3 When macrophages are exposed to zymosan in culture, the cellular activity of pH-4.5 phospholipase A2 is diminished in a manner dependent on zymosan concentration and time of exposure, whereas the cellular activities of pH-8.5 phospholipase A2 and phospholipase C remain unchanged. Zymosan phospholipase A2, group IB, pancreas Mus musculus
4 This release is specifically elicited by an inflammatory substance such as zymosan, since macrophages incubated with 6 micrometer latex spheres retain pH-4.5 phospholipase A2 activity and lysosomal enzyme activities intracellularly. Zymosan phospholipase A2, group IB, pancreas Mus musculus