Title : Effects of liver injury and cholestasis on microsomal enzyme activities and metabolism of halothane, enflurane and methoxyflurane in vivo in rats.

Pub. Date : 1981 May

PMID : 7293219






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Dehalogenation of enflurane, which is the preferred pathway, is affected to the same extent as the cytochrome P-450-dependent hydroxylation of halothane and the O-dealkylation of methoxyflurane. Enflurane cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus