Title : Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system.

Pub. Date : 1981 Mar

PMID : 7265115






1 Functional Relationships(s)
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1 They can oxidize NADH into NAD+ through a nonenzymatic process, and, moreover, quinone from N2-methyl-9-hydroxyellipticine may undergo a nucleophilic attack, resulting in an irreversible binding of the drug to bovine serum albumin. quinone albumin Mus musculus