Title : Arachidonic acid and prostaglandin E2 release and enhanced cell proliferation induced by the phorbol ester TPA in a murine epidermal cell line.

Pub. Date : 1981 Jan

PMID : 7248923






2 Functional Relationships(s)
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1 Addition of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) to a murine epidermal cell line leads to an early induction of the arachidonic acid cascade as measured by the release of [14C]arachidonic acid and [14C]prostaglandin E2 into the medium, to an induction of the ornithine decarboxylase and finally to cell proliferation. Tetradecanoylphorbol Acetate ornithine decarboxylase, structural 1 Mus musculus
2 Addition of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) to a murine epidermal cell line leads to an early induction of the arachidonic acid cascade as measured by the release of [14C]arachidonic acid and [14C]prostaglandin E2 into the medium, to an induction of the ornithine decarboxylase and finally to cell proliferation. Tetradecanoylphorbol Acetate ornithine decarboxylase, structural 1 Mus musculus