Pub. Date : 1980 Aug
PMID : 7207637
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The monoamine oxidase B (MAO-B) selective inhibitor J-508 (N-methyl-N-propargyl-(1-indanyl)-ammonium chloride) appears to interact with MAO-B in a manner consistent with a "suicide" reaction. | N-methyl-N-propargyl-(1-indanyl)-ammonium hydrochloride | monoamine oxidase B | Homo sapiens |
| 2 | The monoamine oxidase B (MAO-B) selective inhibitor J-508 (N-methyl-N-propargyl-(1-indanyl)-ammonium chloride) appears to interact with MAO-B in a manner consistent with a "suicide" reaction. | N-methyl-N-propargyl-(1-indanyl)-ammonium hydrochloride | monoamine oxidase B | Homo sapiens |
| 3 | The monoamine oxidase B (MAO-B) selective inhibitor J-508 (N-methyl-N-propargyl-(1-indanyl)-ammonium chloride) appears to interact with MAO-B in a manner consistent with a "suicide" reaction. | N-methyl-N-propargyl-(1-indanyl)-ammonium hydrochloride | monoamine oxidase B | Homo sapiens |
| 4 | Because of this property, J-508 could be used, under the appropriate conditions, to "titrate" the concentration of MAO-B active centres in the human platelet, although some non-specific binding of this compound to sites other than the active centre of this enzyme form was found, thus limiting the accuracy of the titration method. | N-methyl-N-propargyl-(1-indanyl)-ammonium hydrochloride | monoamine oxidase B | Homo sapiens |