Pub. Date : 1981 Apr-Jun
PMID : 7024393
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Phenformin stimulation of insulin binding to human cultured lymphocytes. | Phenformin | insulin | Homo sapiens |
2 | The effects of the oral hypoglycemic agent, phenformin, were studied on the binding of 125I-insulin to its receptors in IM-9 human cultured lymphocytes. | Phenformin | insulin | Homo sapiens |
3 | Three h after the addition of 5 microgram/ml of phenformin to these cells there was detectable stimulation of 125I-insulin binding; maximal effects were seen after 18 h. A detectable effect of phenformin was seen at 1 microgram/ml and maximal effects were seen at 5 microgram/ml. | Phenformin | insulin | Homo sapiens |
4 | Three h after the addition of 5 microgram/ml of phenformin to these cells there was detectable stimulation of 125I-insulin binding; maximal effects were seen after 18 h. A detectable effect of phenformin was seen at 1 microgram/ml and maximal effects were seen at 5 microgram/ml. | Phenformin | insulin | Homo sapiens |
5 | These studies demonstrate therefore than phenformin increases the binding of 125I-insulin to human cultured lymphocytes, and raise the possibility that phenformin could act in vivo to regulate insulin receptors. | Phenformin | insulin | Homo sapiens |
6 | These studies demonstrate therefore than phenformin increases the binding of 125I-insulin to human cultured lymphocytes, and raise the possibility that phenformin could act in vivo to regulate insulin receptors. | Phenformin | insulin | Homo sapiens |
7 | These studies demonstrate therefore than phenformin increases the binding of 125I-insulin to human cultured lymphocytes, and raise the possibility that phenformin could act in vivo to regulate insulin receptors. | Phenformin | insulin | Homo sapiens |