Title : Time-course of the anti-hypertensive action of atenolol: comparison of response to first dose and to maintained oral administration.

Pub. Date : 1980 Nov

PMID : 7002567






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 After withdrawal of the drug, detectable amounts of atenolol were found in plasma for at least 48 h. The first dose of atenolol caused prompt (3 h) and prolonged (up to 24 h) lowering of supine and standing systolic and diastolic blood pressures, slowing of supine and standing heart rate, reduction of the blood pressure and heart rate responses to dynamic exercise, and a decrease in plasma renin activity. Atenolol renin Homo sapiens
2 After withdrawal of the drug, detectable amounts of atenolol were found in plasma for at least 48 h. The first dose of atenolol caused prompt (3 h) and prolonged (up to 24 h) lowering of supine and standing systolic and diastolic blood pressures, slowing of supine and standing heart rate, reduction of the blood pressure and heart rate responses to dynamic exercise, and a decrease in plasma renin activity. Atenolol renin Homo sapiens