Title : Prostacyclin mediates the potentiated hypotensive effect of bradykinin following captopril treatment.

Pub. Date : 1980 Sep 5

PMID : 6998710






3 Functional Relationships(s)
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1 The effect of angiotensin-converting enzyme inhibition by captopril on the release of a prostacyclin-like substance by bradykinin, angiotensin I and angiotensin II was studied by means of the blood-bathed bioassay technique of Vane. Epoprostenol angiotensinogen Homo sapiens
2 The effect of angiotensin-converting enzyme inhibition by captopril on the release of a prostacyclin-like substance by bradykinin, angiotensin I and angiotensin II was studied by means of the blood-bathed bioassay technique of Vane. Epoprostenol angiotensinogen Homo sapiens
3 Administration of captopril abolished the release of prostacyclin-like substance induced by angiotensin I, potentiated the release provoked by bradykinin and did not alter that due to angiotensin II. Epoprostenol angiotensinogen Homo sapiens